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Tankyrase Inhibitors (TNKS) 49

Tankyrase Inhibitors 49 is a potent and selective small molecule inhibitor of tankyrase with an IC50 of 0.1 nM, demonstrating oral bioavailability. It is a valuable research tool for studying Wnt/β-catenin signaling in cancer biology and has been utilized in both cellular assays and in vivo xenograft models.

Product Specifications

Field of Research

Signal Transduction

Smiles

O=C1NC (SCCC (N[C@H]2CC[C@H] (OC3=CC=C (C#N) C=C3) CC2) =O) =NC4=CC=CC=C41

Molecular Formula

C24H24N4O3S

Molecular Weight

448.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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