BQ-788
BQ-788 is a selective and potent antagonist of the endothelin B (ETB) receptor. It blocks ET-1 binding and its vasoconstrictive effects, as shown in coronary perfusion studies. This compound is widely used in cardiovascular research to investigate endothelin signaling in vitro and in animal models of hypertension.
Product Specifications
CAS Number
173326-37-9
Product Name Alternative
EndothelinReceptor, Endothelin B receptor, Endothelin Receptor, ETB, BQ 788, BQ788, BQ-788
Field of Research
Pharmacology & Drug Discovery
Purity
98.67% (May vary between batches)
Solubility
DMSO:150 mg/mL (233.72 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (7.79 mM)
Smiles
CCCC[C@@H] (NC (=O) [C@@H] (Cc1cn (C (=O) OC) c2ccccc12) NC (=O) [C@H] (CC (C) (C) C) NC (=O) N1[C@@H] (C) CCC[C@H]1C) C (O) =O
Molecular Formula
C34H51N5O7
Molecular Weight
641.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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