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JNJ-42226314

JNJ-42226314 is a potent, selective, and non-covalent inhibitor of monoacylglycerol lipase (MAGL) . Its efficacy in neuropathic and inflammatory pain models is mediated by elevating endogenous 2-arachidonoylglycerol (2-AG) levels, supporting its use in cannabinoid-related in vivo pain research.

Product Specifications

CAS Number

1252765-13-1

Product Name Alternative

JNJ 42226314, JNJ42226314, JNJ-42226314, MAGL

Field of Research

Metabolism Research

Purity

99.62% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.21 mM) ; DMSO:100 mg/mL (204.27 mM)

Smiles

Fc1ccc (cc1) -n1ccc2cc (ccc12) C (=O) N1CC (C1) N1CCN (CC1) C (=O) c1nccs1

Molecular Formula

C26H24FN5O2S

Molecular Weight

489.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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