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TD-0212

TD-0212 is an orally bioavailable small molecule that functions as a dual-acting antagonist of the angiotensin II type 1 receptor (AT1) and an inhibitor of neprilysin (NEP), with respective pKi and pIC50 values of 8.9 and 9.2. This dual pharmacology makes it a valuable research tool for investigating cardiovascular and renal pathophysiology in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1073549-10-6

Field of Research

Metabolism Research

Smiles

C (N1C (CNC ([C@H] (CC (C) C) S) =O) =C (CC) N=C1OCC) C2=C (F) C=C (C=C2) C3=C (C (O) =O) C=CC=C3

Molecular Formula

C28H34FN3O4S

Molecular Weight

527.65

Storage Conditions

-20°C

Notes

For research use only.

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