Apricitabine
Apricitabine (SPD754) is the (-) -enantiomer of dOTC, a potent and selective oral HIV-1 reverse transcriptase inhibitor. It demonstrates significant antiviral activity in clinical studies with a favorable resistance profile and good tolerability in patients, while showing lower affinity for host DNA polymerases.
Product Specifications
CAS Number
160707-69-7
Product Name Alternative
HIV-1 reverse transcriptase, HIVProtease, HIV-1, HIV Protease, AVX 754, AVX754, AVX-754, Apricitabine, DNA Synthesis, DNA polymerase α, DNA polymerase γ, DNA polymerase beta, DNASynthesis, SPD 754, SPD754, SPD-754, RNA Synthesis, RNASynthesis
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry
Purity
99.45% (May vary between batches)
Solubility
DMSO:11 mg/mL (47.98 mM)
Smiles
O=C1N ([C@@H]2S[C@H] (CO) OC2) C=CC (N) =N1
Molecular Formula
C8H11N3O3S
Molecular Weight
229.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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