RO-5328673
RO-5328673 is a high-affinity dual NK2/NK3 receptor antagonist. It exhibits insurmountable antagonism in vitro and demonstrates robust in vivo efficacy, such as reversing senktide-induced locomotor activity in gerbils, making it a valuable research tool for studying neurokinin receptor function in both cellular and animal models.
Product Specifications
CAS Number
1310817-94-7
Smiles
N (C (OC1=CC=C (F) C=C1) =O) (C) [C@H]2[C@@H] (CN (C (=O) C3CCN (C (=O) C4 (C) CC4) CC3) C2) C5=CC (Cl) =C (Cl) C=C5
Molecular Formula
C29H32Cl2FN3O4
Molecular Weight
576.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MPX1454K Each
Magic™ Membrane Protein Human TMEM127 (Transmembrane protein 127) Expressed in vitro E.coli expression system, Full Length
Sign In for Pricing
View Details OR75808-01 1 g
Tert-Butyl4- (pyrimidin-2-yl) piperazine-1-carboxylate
Sign In for Pricing
View Details OR75808-02 25 g
Tert-Butyl4- (pyrimidin-2-yl) piperazine-1-carboxylate
Sign In for Pricing
View Details OR75808-03 100 g
Tert-Butyl4- (pyrimidin-2-yl) piperazine-1-carboxylate
Sign In for Pricing
View Details 