RO-5328673
RO-5328673 is a high-affinity dual NK2/NK3 receptor antagonist. It exhibits insurmountable antagonism in vitro and demonstrates robust in vivo efficacy, such as reversing senktide-induced locomotor activity in gerbils, making it a valuable research tool for studying neurokinin receptor function in both cellular and animal models.
Product Specifications
CAS Number
1310817-94-7
Smiles
N (C (OC1=CC=C (F) C=C1) =O) (C) [C@H]2[C@@H] (CN (C (=O) C3CCN (C (=O) C4 (C) CC4) CC3) C2) C5=CC (Cl) =C (Cl) C=C5
Molecular Formula
C29H32Cl2FN3O4
Molecular Weight
576.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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