AMDE-1
AMDE-1 is a small molecule autophagy inducer that functions in an Atg5-dependent manner. It facilitates the recruitment of Atg16 to pre-autophagosomal structures, leading to LC3 lipidation. This tool compound is utilized in autophagy research for both in vitro and in vivo experimental models.
Product Specifications
CAS Number
478043-30-0
Product Name Alternative
AMDE 1, AMDE1, AMDE-1, Autophagy
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
90.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (6.01 mM) ; DMSO:55 mg/mL (132.3 mM)
Smiles
FC (F) (F) C1=NC2=NC (=CC=C2C (=C1) C (F) (F) F) C (C#N) C1=CC (Cl) =CC=C1
Molecular Formula
C18H8ClF6N3
Molecular Weight
415.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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