Ponatinib Hydrochloride
Ponatinib Hydrochloride is the hydrochloride salt form of ponatinib, a potent multi-targeted kinase inhibitor. It effectively inhibits Abl, PDGFRα, VEGFR2, and other kinases at low nanomolar concentrations and is used in research for studying resistant cancers in both cellular and animal models.
Product Specifications
CAS Number
1114544-31-8
Product Name Alternative
FGFR1, AP 24534, AP 24534 Hydrochloride, AP24534 Hydrochloride, AP-24534 Hydrochloride, VEGFR2, PDGFRα, Ponatinib hydrochloride, Src
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.88% (May vary between batches)
Solubility
DMSO:60 mg/mL (105.44 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.51 mM)
Smiles
Cl.CN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (c3) C#Cc3cnc4cccnn34) cc2C (F) (F) F) CC1
Molecular Formula
C29H28ClF3N6O
Molecular Weight
569.02
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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