BMS-986169
BMS-986169 is a potent and selective negative allosteric modulator targeting the GluN2B subunit of the NMDA receptor, demonstrating an IC50 of 24 nM in oocyte assays. It has shown antidepressant-like efficacy in mouse models, supporting its investigation as a potential therapeutic for treatment-resistant depression.
Product Specifications
CAS Number
1801151-08-5
Product Name Alternative
BMS 986169, BMS986169, BMS-986169
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.61% (May vary between batches)
Smiles
O=C1[C@@H] (CCN1CC2=CC=C (C) C=C2) N3C[C@@H] (F) [C@@H] (CC3) C4=CC=C (O) C=C4
Molecular Formula
C23H27FN2O2
Molecular Weight
382.47
Storage Conditions
-20°C
Notes
For research use only.
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