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BMS-986169

BMS-986169 is a potent and selective negative allosteric modulator targeting the GluN2B subunit of the NMDA receptor, demonstrating an IC50 of 24 nM in oocyte assays. It has shown antidepressant-like efficacy in mouse models, supporting its investigation as a potential therapeutic for treatment-resistant depression.

Product Specifications

CAS Number

1801151-08-5

Product Name Alternative

BMS 986169, BMS986169, BMS-986169

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

97.61% (May vary between batches)

Smiles

O=C1[C@@H] (CCN1CC2=CC=C (C) C=C2) N3C[C@@H] (F) [C@@H] (CC3) C4=CC=C (O) C=C4

Molecular Formula

C23H27FN2O2

Molecular Weight

382.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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