CLK1/2-IN-3
CLK1/2-IN-3 is a selective inhibitor of CLK1 and CLK2 kinases, also affecting SRPK family members. It promotes nuclear speckle enlargement and induces selective splicing of S6K pre-mRNA, leading to antiproliferative effects in various cancer cell lines in vitro.
Product Specifications
CAS Number
1005784-60-0
Product Name Alternative
CLK1/2IN3, CLK-1/2-IN-3, CLK1/2-IN-3, CLK1/2 inhibitor 3, CLK1/2-inhibitor-3, CLK2, CLK1/2 IN 3, CLK1
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
98.71% (May vary between batches)
Solubility
DMSO:3.76 mg/mL (10.02 mM)
Smiles
N (C (=O) C1=CC=C (C (CO) (C) C) C=C1) C2=CN3C (=N2) C=CC (=C3) C=4C=NNC4
Molecular Formula
C21H21N5O2
Molecular Weight
375.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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