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CLK1/2-IN-3

CLK1/2-IN-3 is a selective inhibitor of CLK1 and CLK2 kinases, also affecting SRPK family members. It promotes nuclear speckle enlargement and induces selective splicing of S6K pre-mRNA, leading to antiproliferative effects in various cancer cell lines in vitro.

Product Specifications

CAS Number

1005784-60-0

Product Name Alternative

CLK1/2IN3, CLK-1/2-IN-3, CLK1/2-IN-3, CLK1/2 inhibitor 3, CLK1/2-inhibitor-3, CLK2, CLK1/2 IN 3, CLK1

Field of Research

Cell Biology, Metabolism Research, Signal Transduction

Purity

98.71% (May vary between batches)

Solubility

DMSO:3.76 mg/mL (10.02 mM)

Smiles

N (C (=O) C1=CC=C (C (CO) (C) C) C=C1) C2=CN3C (=N2) C=CC (=C3) C=4C=NNC4

Molecular Formula

C21H21N5O2

Molecular Weight

375.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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