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Cosalane

Cosalane (NSC 658586) is a small molecule inhibitor of HIV replication and CCR7 signaling. It functions by blocking the interaction between the chemokine receptor CCR7 and its ligands CCL19/CCL21. This compound has demonstrated antiviral activity and is utilized in immunological and virological research, including studies on lymphocyte migration and HIV entry mechanisms in vitro.

Product Specifications

CAS Number

154212-56-3

Product Name Alternative

NSC658586, NSC-658586, NSC 640067, NSC 658586, HIV, HIV Protease, HIVProtease, Cosalane

Field of Research

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

98.82% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (4.3 mM) ; DMSO:100 mg/mL (130.23 mM)

Smiles

C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) [C@@] ([C@@H] (CCCC (C) C) C) (CC4) [H]) [H]) (CC[C@]1 (C[C@@H] (CCC=C (C5=CC (C (O) =O) =C (O) C (Cl) =C5) C6=CC (C (O) =O) =C (O) C (Cl) =C6) CC2) [H]) [H]) [H]

Molecular Formula

C45H60Cl2O6

Molecular Weight

767.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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