CRT-0105446
CRT-0105446 is a potent and selective LIM kinase (LIMK) inhibitor. It functions by inhibiting cofilin phosphorylation, which promotes actin depolymerization, and by enhancing α-tubulin acetylation to modulate microtubule stability. This small molecule is a valuable research tool for studying cytoskeleton dynamics in cancer cell migration and neuronal development in vitro.
Product Specifications
CAS Number
1661846-05-4
Field of Research
Cell Biology
Smiles
C (F) (F) (F) C1=C (C=2C (=CC=NC2) C=3SC (NC (C (C) C) =O) =NC3) C=CC (OC) =C1
Molecular Formula
C20H18F3N3O2S
Molecular Weight
421.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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