CRT-0105950
CRT-0105950 is a potent and selective inhibitor of LIMK1 and LIMK2. It modulates cytoskeletal dynamics by inhibiting cofilin phosphorylation and promoting α-tubulin acetylation in cellular studies, making it a useful pharmacological tool for cancer research, including investigations into renal carcinoma.
Product Specifications
CAS Number
1661845-86-8
Product Name Alternative
LIM Kinase, LIMK2, LIMKinase, LIMK1, Microtubule Associated, MicrotubuleAssociated, CRT 0105950, CRT0105950, CRT-0105950, Tubulin
Field of Research
Cell Biology, Signal Transduction
Purity
99.78% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.16 mM) ; DMSO:100 mg/mL (253.88 mM)
Smiles
Cc1ccc (c (Cl) c1) -c1cnccc1-c1cnc (Nc2ccc (O) cc2) s1
Molecular Formula
C21H16ClN3OS
Molecular Weight
393.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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