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CRT-0105950

CRT-0105950 is a potent and selective inhibitor of LIMK1 and LIMK2. It modulates cytoskeletal dynamics by inhibiting cofilin phosphorylation and promoting α-tubulin acetylation in cellular studies, making it a useful pharmacological tool for cancer research, including investigations into renal carcinoma.

Product Specifications

CAS Number

1661845-86-8

Product Name Alternative

LIM Kinase, LIMK2, LIMKinase, LIMK1, Microtubule Associated, MicrotubuleAssociated, CRT 0105950, CRT0105950, CRT-0105950, Tubulin

Field of Research

Cell Biology, Signal Transduction

Purity

99.78% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.16 mM) ; DMSO:100 mg/mL (253.88 mM)

Smiles

Cc1ccc (c (Cl) c1) -c1cnccc1-c1cnc (Nc2ccc (O) cc2) s1

Molecular Formula

C21H16ClN3OS

Molecular Weight

393.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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