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DA-11004

DA-11004 is a potent and selective inhibitor of NADP-dependent isocitrate dehydrogenase (IDPc), exhibiting an IC50 of 1.49 μM. This small molecule has been shown to suppress fatty acid synthesis in adipose tissue and, in a mouse model of high-fat diet-induced obesity, reduced both plasma glucose and free fatty acid levels.

Product Specifications

CAS Number

57404-51-0

Smiles

O=C1C=2C (C (NC) =CC1=O) =CC=CC2

Molecular Formula

C11H9NO2

Molecular Weight

187.19

Storage Conditions

-20°C

Notes

For research use only.

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