FzM1
FzM1 is a negative allosteric modulator of FZD4 that binds intracellularly to ICL3, inhibiting WNT5A-driven WNT/β-catenin signaling with a log EC50inh of -6.2. This small molecule is a valuable research tool for investigating FZD4 function in both cellular and animal models of development and disease.
Product Specifications
CAS Number
1680196-54-6
Product Name Alternative
Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin, beta-catenin, betacatenin, bcatenin, FZD4, FzM 1, FzM1, FzM-1
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.37% (May vary between batches)
Solubility
DMSO:65 mg/mL (180.34 mM)
Smiles
Oc1cc (NC (=O) Nc2ccc3ccccc3c2) cc (c1) -c1cccs1
Molecular Formula
C21H16N2O2S
Molecular Weight
360.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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