GGTI-2133
GGTI-2133 is a potent and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase-I), exhibiting an IC50 of 38 nM. This compound has been shown to reduce inflammatory cell infiltration in murine models of asthma, supporting its use in researching protein prenylation, cell signaling, and inflammatory diseases in both in vitro and in vivo contexts.
Product Specifications
CAS Number
191102-79-1
Product Name Alternative
GGTase I, GGTI 2133, GGTI2133, GGTI-2133
Field of Research
Metabolism Research
Purity
99.47% (May vary between batches)
Solubility
DMSO:50 mg/mL (109.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM)
Smiles
C (N[C@@H] (CC (C) C) C (O) =O) (=O) C1=C (C=2C3=C (C=CC2) C=CC=C3) C=C (NCC4=CN=CN4) C=C1
Molecular Formula
C27H28N4O3
Molecular Weight
456.54
Storage Conditions
-20°C
Notes
For research use only.
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