GSK854
GSK854 is a potent and selective TNNI3K inhibitor. It reduces oxidative stress and limits cardiomyocyte pyroptosis and apoptosis following myocardial infarction in mice, thereby attenuating adverse cardiac remodeling. This small molecule is a valuable research tool for studying ischemic heart disease in both in vitro and in vivo models.
Product Specifications
CAS Number
1316059-00-3
Product Name Alternative
Apoptosis, GSK 854, GSK854, GSK-854, TNNI3 Interacting Kinase (TNNI3K)
Field of Research
Cell Biology, Signal Transduction
Purity
98.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.28 mM) ; DMSO:100 mg/mL (207.06 mM)
Smiles
CCS (=O) (=O) c1ccc (cc1Nc1cc (Nc2ccc (Cl) cn2) ncn1) S (=O) (=O) NC
Molecular Formula
C18H19ClN6O4S2
Molecular Weight
482.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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