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GW648495

GW648495 is a potent and selective inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), exhibiting over 4,000-fold selectivity for the malarial enzyme versus the human counterpart. This compound is a valuable chemical tool for studying malaria parasite biology and has demonstrated antiplasmodial activity in both in vitro and in vivo research models.

Product Specifications

CAS Number

92872-51-0

Field of Research

Infectious Disease & Virology, Metabolism Research

Smiles

N (C=1N2C (N=C (C) C1) =NC=N2) C3=CC4=C (C=C3) C=CC=C4

Molecular Formula

C16H13N5

Molecular Weight

275.31

Storage Conditions

-20°C

Notes

For research use only.

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