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HCI-2184

HCI-2184 is a dual inhibitor targeting AXL kinase and Nek2, developed to overcome bortezomib resistance in multiple myeloma. It has demonstrated efficacy in both in vitro cell-based assays and in vivo xenograft models, making it a valuable research tool for investigating drug-resistant cancer mechanisms.

Product Specifications

CAS Number

1341200-61-0

Field of Research

Cancer Biology, Signal Transduction

Smiles

S (N (C) C) (=O) (=O) C1=C (NC2=NC (NC3=CC=C (C=C3) N4CCN (C) CC4) =NC=C2Cl) C=CC=C1

Molecular Formula

C23H28ClN7O2S

Molecular Weight

502.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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