HCI-2184
HCI-2184 is a dual inhibitor targeting AXL kinase and Nek2, developed to overcome bortezomib resistance in multiple myeloma. It has demonstrated efficacy in both in vitro cell-based assays and in vivo xenograft models, making it a valuable research tool for investigating drug-resistant cancer mechanisms.
Product Specifications
CAS Number
1341200-61-0
Field of Research
Cancer Biology, Signal Transduction
Smiles
S (N (C) C) (=O) (=O) C1=C (NC2=NC (NC3=CC=C (C=C3) N4CCN (C) CC4) =NC=C2Cl) C=CC=C1
Molecular Formula
C23H28ClN7O2S
Molecular Weight
502.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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