KLH45
KLH45 is a potent and selective small molecule inhibitor of the triglyceride hydrolase DDHD2 (SPG54), exhibiting an IC50 of 1.3 nM. This compound is a valuable chemical probe for investigating lipid metabolism and the pathogenesis of hereditary spastic paraplegia in both cellular and animal model studies.
Product Specifications
CAS Number
1632236-44-2
Product Name Alternative
DDHD2, KLH 45, KLH45, KLH-45
Field of Research
Metabolism Research
Purity
99.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.91 mM) ; DMSO:162 mg/mL (353.34 mM)
Smiles
FC (F) (F) Oc1ccc (cc1) -c1cnn (n1) C (=O) N (CCc1ccccc1) C1CCCCC1
Molecular Formula
C24H25F3N4O2
Molecular Weight
458.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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