7-BIA
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM[1].
Product Specifications
CAS Number
[1313403-49-4]
Product Name Alternative
LCB01-0371
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-bia.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)
Smiles
O=CC1=C(C2=CC(OCCCC)=C1OC)CC(O)OC2=O
Molecular Formula
C15H18O6
Molecular Weight
294.30
References & Citations
[1]Uhl GR, et al. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosinephosphatase D (PTPRD) and by a novel PTPRD antagonist. Proc Natl Acad Sci U S A. 2018 Nov 6;115 (45) :11597-11602.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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