NPD-001
NPD-001 is a potent small molecule inhibitor of TbrPDEB1, a target for African sleeping sickness, with an IC50 of 4 nM. It exhibits greater potency against human PDE4B1 (IC50 = 0.6 nM) . This compound is a valuable research tool for studying phosphodiesterase function in both parasitic and mammalian systems in vitro.
Product Specifications
CAS Number
469863-16-9
Field of Research
Infectious Disease & Virology, Metabolism Research
Smiles
O=C1[C@]2 ([C@@] (C (=NN1C3CCCCCC3) C4=CC (OCCCCOC5=CC=C (C=C5) C=6NN=NN6) =C (OC) C=C4) (CC=CC2) [H]) [H]
Molecular Formula
C33H40N6O4
Molecular Weight
584.71
Storage Conditions
-20°C
Notes
For research use only.
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