Pegamotecan
Pegamotecan is a polyethylene glycol-conjugated camptothecin derivative that acts as a topoisomerase I inhibitor. It has demonstrated anticancer activity in preclinical in vitro and in vivo studies, supporting its research for treating solid tumors such as esophageal, non-small cell lung, and pancreatic cancers.
Product Specifications
CAS Number
581079-18-7
Product Name Alternative
PEG-camptothecin, PEG-b-CPT, PEG-beta-CPT, Pegamotecan, PEG-β-CPT, topoisomerase I, Prothecan
Field of Research
Molecular Biology
Purity
96.40% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (16.99 mM)
Smiles
CC[C@@]1 (OC (=O) [C@H] (C) NC (=O) COCCOCC (=O) N[C@@H] (C) C (=O) O[C@]2 (CC) C (=O) OCc3c2cc2-c4nc5ccccc5cc4Cn2c3=O) C (=O) OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O
Molecular Formula
C52H48N6O14
Molecular Weight
980.984
Storage Conditions
-20°C
Notes
For research use only.
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