PKR-IN-C51
PKR-IN-C51 is a dose-dependent, ATP-competitive inhibitor of the interferon-induced kinase PKR, with a Ki of 3.4 μM. It effectively blocks PKR autophosphorylation and activation in cellular models like macrophages, making it a valuable research tool for studying PKR's role in viral infection, inflammation, and cellular stress responses in vitro.
Product Specifications
CAS Number
1314594-23-4
Product Name Alternative
PKRINC 51, PKRINC51, PKR-IN-C51, PKR-IN-C-51, PKRINC-51, PKR-inhibitor-C51, PKR IN C51, PKR inhibitor C51
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction
Purity
98.94% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.89 mM) ; DMSO:100 mg/mL (272.15 mM)
Smiles
N1=CC=C (N=C1NCCC2=CNC=3C=CC=CC32) C=4C=5C=CC=CC5NC4C
Molecular Formula
C23H21N5
Molecular Weight
367.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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