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Poloppin

Poloppin is a small molecule modulator of mitotic polo-like kinases that targets mutant KRAS, acting synergistically with the c-MET inhibitor Crizotinib against KRAS-mutant cancer cells. It is applied in oncology research, with in vitro and in vivo studies exploring its efficacy in targeted therapy development.

Product Specifications

CAS Number

683808-78-8

Field of Research

Cell Biology, Signal Transduction

Smiles

OC (=O) CCC1=CC=C (N1C1=C (C=CC=C1) C (F) (F) F) C1=CC=C (Br) C=C1

Molecular Formula

C20H15BrF3NO2

Molecular Weight

438.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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