Poloppin
Poloppin is a small molecule modulator of mitotic polo-like kinases that targets mutant KRAS, acting synergistically with the c-MET inhibitor Crizotinib against KRAS-mutant cancer cells. It is applied in oncology research, with in vitro and in vivo studies exploring its efficacy in targeted therapy development.
Product Specifications
CAS Number
683808-78-8
Field of Research
Cell Biology, Signal Transduction
Smiles
OC (=O) CCC1=CC=C (N1C1=C (C=CC=C1) C (F) (F) F) C1=CC=C (Br) C=C1
Molecular Formula
C20H15BrF3NO2
Molecular Weight
438.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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