Hh-Ag1.5
Hh-Ag1.5 is a potent small molecule agonist of the Hedgehog pathway and Smoothened receptor (EC50: 1 nM) . It is used in research to study stem cell biology, enabling the differentiation of hiPSCs into neural and skin lineages in vitro and demonstrating hepatoprotective effects in models of liver failure.
Product Specifications
CAS Number
612542-14-0
Product Name Alternative
Hedgehog, Hh Ag1.5, HhAg1.5, Hh-Ag1.5, Hh-Ag-1.5, SAG 1.5, SAG1.5, SAG-1.5, Smoothened
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.61% (May vary between batches)
Solubility
DMSO:26.3 mg/mL (50 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.8 mM)
Smiles
CN[C@H]1CC[C@@H] (CC1) N (Cc1cccc (c1) -c1ccncc1) C (=O) c1sc2c (F) ccc (F) c2c1Cl
Molecular Formula
C28H26ClF2N3OS
Molecular Weight
526.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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