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Scaff10-8

Scaff10-8 is a small molecule inhibitor that disrupts the AKAP-Lbc/RhoA interaction. This action promotes aquaporin-2 membrane trafficking in renal principal cells, making it a valuable research tool for studying cAMP-independent AQP2 regulation, Rho signaling pathways, and potential mechanisms of nephrogenic diabetes insipidus in cellular models.

Product Specifications

CAS Number

777857-56-4

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

COC1=CC=C (C=C1) C1=COC2=C1C=C1C (OC (=O) C (CCC (O) =O) =C1C) =C2

Molecular Formula

C22H18O6

Molecular Weight

378.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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