Scaff10-8
Scaff10-8 is a small molecule inhibitor that disrupts the AKAP-Lbc/RhoA interaction. This action promotes aquaporin-2 membrane trafficking in renal principal cells, making it a valuable research tool for studying cAMP-independent AQP2 regulation, Rho signaling pathways, and potential mechanisms of nephrogenic diabetes insipidus in cellular models.
Product Specifications
CAS Number
777857-56-4
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
COC1=CC=C (C=C1) C1=COC2=C1C=C1C (OC (=O) C (CCC (O) =O) =C1C) =C2
Molecular Formula
C22H18O6
Molecular Weight
378.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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