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Stafib-1

Stafib-1 is a potent and selective STAT5β inhibitor that targets its SH2 domain, exhibiting an IC50 of 154 nM and a Ki of 44 nM. This small molecule is a valuable research tool for studying STAT5β-dependent signaling in cancer and hematopoiesis, with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1688703-26-5

Product Name Alternative

Inhibitor, inhibit, K562, STAT5β, STAT5b, Stafib 1, Stafib1, Stafib-1, STAT

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

97.18% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.48 mM) ; DMSO:95 mg/mL (157.7 mM)

Smiles

O (P (=O) (O) O) C1=C (OP (=O) (O) O) C=CC (CNC (COC2=CC3=C (C=C2) C=C (C (NC4=CC=CC=C4) =O) C=C3) =O) =C1

Molecular Formula

C26H24N2O11P2

Molecular Weight

602.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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