Stafib-1
Stafib-1 is a potent and selective STAT5β inhibitor that targets its SH2 domain, exhibiting an IC50 of 154 nM and a Ki of 44 nM. This small molecule is a valuable research tool for studying STAT5β-dependent signaling in cancer and hematopoiesis, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1688703-26-5
Product Name Alternative
Inhibitor, inhibit, K562, STAT5β, STAT5b, Stafib 1, Stafib1, Stafib-1, STAT
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
97.18% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.48 mM) ; DMSO:95 mg/mL (157.7 mM)
Smiles
O (P (=O) (O) O) C1=C (OP (=O) (O) O) C=CC (CNC (COC2=CC3=C (C=C2) C=C (C (NC4=CC=CC=C4) =O) C=C3) =O) =C1
Molecular Formula
C26H24N2O11P2
Molecular Weight
602.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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