TFC-007
TFC-007 is a potent and selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS), effectively suppressing inflammatory mediators. It serves as a key precursor for synthesizing H-PGDS-targeting PROTAC degraders and has been utilized in research models, such as cedar pollen-induced allergic rhinitis in guinea pigs, to study allergic inflammation pathways.
Product Specifications
CAS Number
927878-49-7
Product Name Alternative
TFC 007, TFC007, TFC-007
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.07% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C (NC1=CC=C (C=C1) N2CCC (C (=O) N3CCOCC3) CC2) C4=CN=C (N=C4) OC=5C=CC=CC5
Molecular Formula
C27H29N5O4
Molecular Weight
487.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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