TFMB- (S) -2-HG
TFMB- (S) -2-Hydroxyglutarate is a potent cell-permeable inhibitor of both TET2 and EglN prolyl hydroxylases. Its application in AML research is supported by studies demonstrating its ability to modulate DNA and histone methylation in vitro, offering a tool to investigate epigenetic dysregulation in leukemia models.
Product Specifications
CAS Number
1445703-64-9
Product Name Alternative
DNA Methyltransferase, DNAMethyltransferase, TET2, TFMB 2 HG, TFMB (S) 2 HG, TFMB S 2 HG, TFMB (S) 2HG, TFMB2HG, TFMB-2-HG, TFMB-S-2-HG
Field of Research
Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.07% (May vary between batches)
Solubility
DMSO:60 mg/mL (208.17 mM) ;10% DMSO+90% Saline:2.5 mg/mL (8.67 mM)
Smiles
FC (F) (F) c1cccc (COC (=O) [C@@H]2CCC (=O) O2) c1
Molecular Formula
C13H11F3O4
Molecular Weight
288.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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