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3'-Fluoroaminopterin

3'-Fluoroaminopterin is a potent antifolate agent that acts as a folic acid antagonist. It is widely used in biochemical research to inhibit dihydrofolate reductase (DHFR), facilitating studies in cancer research, enzymology, and both in vitro and in vivo investigations of cell proliferation and chemotherapy mechanisms.

Product Specifications

CAS Number

85803-34-5

Smiles

NC=1C2=C (N=CC (CNC3=C (F) C=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =N2) N=C (N) N1

Molecular Formula

C19H19FN8O5

Molecular Weight

458.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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