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Cediranib maleate

Cediranib maleate (AZD2171 maleate) is an orally bioavailable, potent inhibitor targeting VEGFR2 and other key tyrosine kinases like PDGFR and c-Kit. It has been studied in ovarian cancer models, where it demonstrates anti-angiogenic activity and can upregulate MHC-I expression through transcriptional mechanisms in both in vitro and in vivo settings.

Product Specifications

CAS Number

857036-77-2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

C (=C\C (O) =O) \C (O) =O.O (C=1C2=C (C=C (OCCCN3CCCC3) C (OC) =C2) N=CN1) C=4C (F) =C5C (=CC4) NC (C) =C5

Molecular Formula

C29H31FN4O7

Molecular Weight

566.58

Storage Conditions

-20°C

Notes

For research use only.

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