Cediranib maleate
Cediranib maleate (AZD2171 maleate) is an orally bioavailable, potent inhibitor targeting VEGFR2 and other key tyrosine kinases like PDGFR and c-Kit. It has been studied in ovarian cancer models, where it demonstrates anti-angiogenic activity and can upregulate MHC-I expression through transcriptional mechanisms in both in vitro and in vivo settings.
Product Specifications
CAS Number
857036-77-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (=C\C (O) =O) \C (O) =O.O (C=1C2=C (C=C (OCCCN3CCCC3) C (OC) =C2) N=CN1) C=4C (F) =C5C (=CC4) NC (C) =C5
Molecular Formula
C29H31FN4O7
Molecular Weight
566.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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