AZD8309
AZD8309 is a potent and orally bioavailable CXCR2 antagonist that modulates neutrophil migration. It has demonstrated efficacy in reducing pancreatic and pulmonary myeloperoxidase (MPO) and decreasing pancreatic protease activity in preclinical models, supporting its use in researching neutrophilic inflammatory diseases.
Product Specifications
CAS Number
333742-48-6
Product Name Alternative
AZD 8309, AZD8309, AZD-8309, CXCR2, GlutathionePeroxidase, Glutathione Peroxidase, MPO
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.35% (May vary between batches)
Solubility
DMSO:65 mg/mL (169.09 mM)
Smiles
N ([C@@H] (CO) C) C1=C2C (=NC (SCC3=C (F) C (F) =CC=C3) =N1) NC (=O) S2
Molecular Formula
C15H14F2N4O2S2
Molecular Weight
384.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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