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AZD8309

AZD8309 is a potent and orally bioavailable CXCR2 antagonist that modulates neutrophil migration. It has demonstrated efficacy in reducing pancreatic and pulmonary myeloperoxidase (MPO) and decreasing pancreatic protease activity in preclinical models, supporting its use in researching neutrophilic inflammatory diseases.

Product Specifications

CAS Number

333742-48-6

Product Name Alternative

AZD 8309, AZD8309, AZD-8309, CXCR2, GlutathionePeroxidase, Glutathione Peroxidase, MPO

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Purity

98.35% (May vary between batches)

Solubility

DMSO:65 mg/mL (169.09 mM)

Smiles

N ([C@@H] (CO) C) C1=C2C (=NC (SCC3=C (F) C (F) =CC=C3) =N1) NC (=O) S2

Molecular Formula

C15H14F2N4O2S2

Molecular Weight

384.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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