CL67
CL67 is a small molecule inhibitor of the hypoxia-inducible factor (HIF) pathway. It functions by selectively binding to and stabilizing a G-quadruplex structure within the HIF-1α promoter, thereby suppressing its transcriptional activity in vitro. This mechanism makes it a valuable chemical probe for studying hypoxia signaling in cancer and cardiovascular research.
Product Specifications
CAS Number
1401242-86-1
Field of Research
Epigenetics & Chromatin, Metabolism Research
Smiles
N (C (CN (CC) CC) =O) C=1C=C (N2C=C (C3=CC4=C (C=CC (=C4) C5=CN (N=N5) C6=CC (NC (CN (CC) CC) =O) =CC=C6) C=C3) N=N2) C=CC1
Molecular Formula
C38H42N10O2
Molecular Weight
670.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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