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Dalvastatin

Dalvastatin (RG-12561) is an orally bioavailable HMG-CoA reductase inhibitor that lowers cholesterol synthesis. It competitively inhibits rat hepatic HMG-CoA reductase with an IC50 of 3.4 nM and shows an ED50 of 0.9 mg/kg for inhibiting cholesterol biosynthesis in rat liver sections in vivo.

Product Specifications

CAS Number

132100-55-1

Product Name Alternative

Dalvastatin, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), HMGCoAReductase, RG12561, RG-12561, RG 12561

Field of Research

Metabolism Research

Purity

98.07% (May vary between batches)

Solubility

DMSO:50 mg/mL (129.37 mM)

Smiles

C (=C/[C@H]1C[C@H] (O) CC (=O) O1) \C2=C (CC (C) (C) CC2 (C) C) C3=CC (C) =C (F) C=C3

Molecular Formula

C24H31FO3

Molecular Weight

386.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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