Dalvastatin
Dalvastatin (RG-12561) is an orally bioavailable HMG-CoA reductase inhibitor that lowers cholesterol synthesis. It competitively inhibits rat hepatic HMG-CoA reductase with an IC50 of 3.4 nM and shows an ED50 of 0.9 mg/kg for inhibiting cholesterol biosynthesis in rat liver sections in vivo.
Product Specifications
CAS Number
132100-55-1
Product Name Alternative
Dalvastatin, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), HMGCoAReductase, RG12561, RG-12561, RG 12561
Field of Research
Metabolism Research
Purity
98.07% (May vary between batches)
Solubility
DMSO:50 mg/mL (129.37 mM)
Smiles
C (=C/[C@H]1C[C@H] (O) CC (=O) O1) \C2=C (CC (C) (C) CC2 (C) C) C3=CC (C) =C (F) C=C3
Molecular Formula
C24H31FO3
Molecular Weight
386.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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