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Dihydrohomofolic acid

Dihydrohomofolic acid is a reductase substrate converted to tetrahydrohomofolate, an inhibitor of thymidylate synthase. This mechanism allows it to suppress DNA synthesis, making it a useful research tool for studying antifolate activity and nucleotide metabolism in both cellular and biochemical assays.

Product Specifications

CAS Number

14866-11-6

Smiles

O=C1C2=C (NCC (CCNC3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =N2) NC (N) =N1

Molecular Formula

C20H23N7O6

Molecular Weight

457.44

Storage Conditions

-20°C

Notes

For research use only.

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