Filanesib TFA
Filanesib (ARRY-520) is a selective inhibitor of the mitotic kinesin KSP (Eg5), which induces mitotic arrest and apoptosis in proliferating cancer cells. Its research applications include investigating cell cycle mechanisms in vitro and evaluating antitumor efficacy in xenograft models, as documented in oncology and pharmacology studies.
Product Specifications
CAS Number
1781834-99-8
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
C (C (O) =O) (F) (F) F.C (CCN) [C@@]1 (N (C (N (OC) C) =O) N=C (S1) C2=C (F) C=CC (F) =C2) C3=CC=CC=C3
Molecular Formula
C22H23F5N4O4S
Molecular Weight
534.5
Storage Conditions
-20°C
Notes
For research use only.
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