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ICI 198583

ICI 198583 is a small molecule inhibitor targeting thymidylate synthase, a key enzyme in folate metabolism. This compound is utilized in biochemical and cancer research to study nucleotide biosynthesis inhibition, with applications in both in vitro enzymatic assays and in vivo models of proliferative diseases.

Product Specifications

CAS Number

112887-62-4

Smiles

O=C1C=2C (=CC=C (CN (CC#C) C3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) C2) NC (C) =N1

Molecular Formula

C25H24N4O6

Molecular Weight

476.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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