ICI 198583
ICI 198583 is a small molecule inhibitor targeting thymidylate synthase, a key enzyme in folate metabolism. This compound is utilized in biochemical and cancer research to study nucleotide biosynthesis inhibition, with applications in both in vitro enzymatic assays and in vivo models of proliferative diseases.
Product Specifications
CAS Number
112887-62-4
Smiles
O=C1C=2C (=CC=C (CN (CC#C) C3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) C2) NC (C) =N1
Molecular Formula
C25H24N4O6
Molecular Weight
476.48
Storage Conditions
-20°C
Notes
For research use only.
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