Pyrithione
Pyrithione is an inhibitor of membrane transport processes in fungi. Pyrithione is a potent antibiotic aspergillic acid. Pyrithion incubated Penicillium mycelia would have a marked decrease in the activities of a variety of independently regulated transport systems[1].
Product Specifications
CAS Number
[1121-30-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pyrithione.html
Purity
99.75
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
S=C1C=CC=CN1O
Molecular Formula
C5H5NOS
Molecular Weight
127.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Chandler, C. J., & Segel, I. H. (1978) . Mechanism of the antimicrobial action of pyrithione: effects on membrane transport, ATP levels, and protein synthesis. Antimicrobial agents and chemotherapy, 14 (1), 60–68.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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